Partner: O. Warszawik-Hendzel


Recent publications
1.Maj M., Warszawik-Hendzel O., Szymańska E., Walecka I., Rakowska A., Antczak-Marczak M., Kuna P., Kruszewski J., Nasierowska-Guttmejer A., Litniewski J., Nowicki A., Olszewska M., Rudnicka L., High frequency ultrasonography: a complementary diagnostic method in evaluation of primary cutaneous melanoma, GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA, ISSN: 0392-0488, Vol.150, No.5, pp.595-601, 2015
Abstract:

Aim.
The aim of our study was to assess the usefulness of high frequency ultrasonography in the diagnosis of melanoma. Methods. We examined 84 patients with suspicious melanocytic skin lesions, including 19 cases of melanoma. In vivo high-resolution ultrasonography (30 MHz) was performed prior to excision.

Results.
In ultrasound scans early melanomas presented as flat oval or fusiform shaped structures and were clearly demarcated, while advanced melanomas were characterized by a roundish shape with less distinct borders. The ultrasonographic thickness of in situ melanomas ranged from 0.02 to 0.85 mm. In the case of invasive tumors, the mean thickness evaluated by high frequency ultrasonography was 10.7% higher compared to the Breslow Score (1.44±0.8 mm and 1.3±0.88 mm, respectively). In all melanomas of Breslow Score of 1 mm or more ultrasound also indicated a Breslow Score of 1 mm or more.

Conclusion.
High frequency ultrasound examination has limited value in differential diagnosis of melanoma, but it gives a clear picture of the size and depth of the tumor. The method should be used as a complementary method (after dermoscopy and, where applicable, reflectance confocal microscopy) in preoperative evaluation of the tumor. In some cases of locally advanced melanoma, ultrasound examination may allow to reduce the number of surgical procedures and favor the decision of a one-time surgical treatment (removal of primary tumor and sentinel lymph node biopsy at the same time).

Keywords:

Dermoscopy - Diagnosis - Melanoma - Microscopy, confocal - Ultrasonography

Affiliations:
Maj M.-Medical University of Warsaw (PL)
Warszawik-Hendzel O.-other affiliation
Nowicki A.-IPPT PAN
Olszewska M.-other affiliation
Rudnicka L.-Medical University of Warsaw (PL)
Szymańska E.-other affiliation
Walecka I.-other affiliation
Rakowska A.-other affiliation
Antczak-Marczak M.-Medical University of Lodz (PL)
Kuna P.-Medical University of Lodz (PL)
Kruszewski J.-other affiliation
Nasierowska-Guttmejer A.-Central Clinical Hospital MSW (PL)
Litniewski J.-IPPT PAN