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1.Nowicki A., Trawiński Z., Gambin B., Secomski W., Szubielski M., Parol M., Olszewski R., 20-MHZ ultrasound for measurements offlow-mediated dilation and shear rate in the radialartery , ULTRASOUND IN MEDICINE AND BIOLOGY, ISSN: 0301-5629, DOI: 10.1016/j.ultrasmedbio.2018.02.011, Vol.44, No.6, pp.1187-1197, 2018
Nowicki A., Trawiński Z., Gambin B., Secomski W., Szubielski M., Parol M., Olszewski R., 20-MHZ ultrasound for measurements offlow-mediated dilation and shear rate in the radialartery , ULTRASOUND IN MEDICINE AND BIOLOGY, ISSN: 0301-5629, DOI: 10.1016/j.ultrasmedbio.2018.02.011, Vol.44, No.6, pp.1187-1197, 2018

Abstract:
A high-frequency scanning system consisting of a 20-MHz linear array transducer combined with a 20-MHz pulsed Dopplerprobe was introduced to evaluate the degree of radial artery flow-mediated dilation (FMD [%]) in two groups of patients after5 min of controlled forearm ischemia followed by reactive hyperemia. In group I, comprising 27 healthy volunteers, FMD (mean ± standard deviation) was 15.26 ± 4.90% (95% confidence interval [CI]: 13.32%–17.20%); in group II, comprising 17 patients with chronic coronary artery disease, FMD was significantly less at 4.53 ± 4.11% (95% CI: 2.42%–6.64%). Specifically, the ratio FMD/SR (mean ± standard deviation),wasequalto5.36×10−4±4.64×10−4 (95%CI:3.54×10−4 to7.18×10−4)ingroupIand1.38×10−4±0.89×10−4 (95% CI: 0.70 × 10−4 to 2.06 × 10−4) in group II. Statistically significant differences between the two groups were confirmed by a Wilcoxon–Mann–Whitney test for both FMD and FMD/SR (p < 0.01). Areas under receiver operating characteristic curves for FMD and FMD/SR were greater than 0.9. The results confirm the usefulness of the proposed measurements of radial artery FMD and SR in differentiation of normal patients from those with chronic coronary artery disease. (E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ) © 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Keywords:
Flow-mediated vasodilation, Radial artery, Shear rate, Reactive hyperemia, Endothelium, Pulsed doppler, Ultrasonography

2.Tasinkiewicz J., Falińska K., Lewin P., Litniewski J., Improving broadband ultrasound attenuation assessment in cancellous bone by mitigating the influence of cortical bone: Phantom and in-vitro study, Ultrasonics, ISSN: 0041-624X, DOI: 10.1016/j.ultras.2018.06.018, Vol.92, pp.1-7, 2018
Tasinkiewicz J., Falińska K., Lewin P., Litniewski J., Improving broadband ultrasound attenuation assessment in cancellous bone by mitigating the influence of cortical bone: Phantom and in-vitro study, Ultrasonics, ISSN: 0041-624X, DOI: 10.1016/j.ultras.2018.06.018, Vol.92, pp.1-7, 2018

Abstract:
The purpose of this work was to present a new approach that allows the influence of cortical bone on noninvasive measurement of broadband ultrasound attenuation (BUA) to be corrected. The method, mplemented here at 1 MHz makes use of backscattered signal and once refined and clinically confirmed, it would offer an alternative to ionizing radiation based methods, such as DEXA (Dual-nergy X-ray absorptiometry), quantitative computed tomography (QCT), radiographic absorptiometry (RA) or single X-ray absorptiometry (SXA), which are clinically approved for assessment of progress of osteoporosis. In addition, as the method employs reflected waves, it might substantially enhance the applicability of BUA - from being suitable to peripheral bones only it would extend this applicability to include such embedded bones as hip and femoral neck. The proposed approach allows the cortical layer parameters used for correction and the corrected value and parameter of the ancellous bone (BUA) to be determined simultaneously from the single (pulse-echo) bone backscattered wave; to the best of the authors’ knowledge such approach was not previously reported. The validity of the method was tested using acoustic data obtained from a custom- esigned bone-mimicking phantom and a calf femur. The relative error of the attenuation coefficient assessment was determined to be 3.9% and 4.7% for the bone phantom and calf bone specimens, respectively. When the cortical shell influence was not taken into account the corresponding errors were considerably higher 8.3% (artificial bone) and 9.2% (calf femur). As indicated above, once clinically proven, the use of this BUA measurement technique in reflection mode would augment diagnostic power of the attending physician by permitting to include bones, which are not accessible for transmission mode evaluation, e.g. hip, spine, humerus and femoral neck.

Keywords:
Broadband ultrasound attenuation, Correction of influence of cortical bone, Trabecular bone