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1.Nowicki A., Trawiński Z., Gambin B., Secomski W., Szubielski M., Parol M., Olszewski R., 20-MHZ ULTRASOUND FOR MEASUREMENTS OFFLOW-MEDIATED DILATION AND SHEAR RATE IN THE RADIALARTERY , ULTRASOUND IN MEDICINE AND BIOLOGY, ISSN: 0301-5629, DOI: 10.1016/j.ultrasmedbio.2018.02.011, Vol.44, No.6, pp.1187-1197, 2018
Nowicki A., Trawiński Z., Gambin B., Secomski W., Szubielski M., Parol M., Olszewski R., 20-MHZ ULTRASOUND FOR MEASUREMENTS OFFLOW-MEDIATED DILATION AND SHEAR RATE IN THE RADIALARTERY , ULTRASOUND IN MEDICINE AND BIOLOGY, ISSN: 0301-5629, DOI: 10.1016/j.ultrasmedbio.2018.02.011, Vol.44, No.6, pp.1187-1197, 2018

Abstract:
A high-frequency scanning system consisting of a 20-MHz linear array transducer combined with a 20-MHz pulsed Dopplerprobe was introduced to evaluate the degree of radial artery flow-mediated dilation (FMD [%]) in two groups of patients after5 min of controlled forearm ischemia followed by reactive hyperemia. In group I, comprising 27 healthy volunteers, FMD (mean ± standard deviation) was 15.26 ± 4.90% (95% confidence interval [CI]: 13.32%–17.20%); in group II, comprising 17 patients with chronic coronary artery disease, FMD was significantly less at 4.53 ± 4.11% (95% CI: 2.42%–6.64%). Specifically, the ratio FMD/SR (mean ± standard deviation),wasequalto5.36×10−4±4.64×10−4 (95%CI:3.54×10−4 to7.18×10−4)ingroupIand1.38×10−4±0.89×10−4 (95% CI: 0.70 × 10−4 to 2.06 × 10−4) in group II. Statistically significant differences between the two groups were confirmed by a Wilcoxon–Mann–Whitney test for both FMD and FMD/SR (p < 0.01). Areas under receiver operating characteristic curves for FMD and FMD/SR were greater than 0.9. The results confirm the usefulness of the proposed measurements of radial artery FMD and SR in differentiation of normal patients from those with chronic coronary artery disease. (E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ) © 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Keywords:
Flow-mediated vasodilation, Radial artery, Shear rate, Reactive hyperemia, Endothelium, Pulsed doppler, Ultrasonography