Beata Niemczyk, M.Sc., Eng.

Laboratory of Polymers and Biomaterials (SPPiB)
position: doctoral student
telephone: (+48) 22 826 12 81 ext.: 171
room: 334
e-mail: bniem

Recent publications
1.Niemczyk B., Sajkiewicz P.Ł., Kołbuk D., Injectable hydrogels as novel materials for central nervous system regeneration, Journal of neural engineering, ISSN: 1741-2560, DOI: 10.1088/1741-2552/aacbab, Vol.15, No.5, pp.051002-1-15, 2018
Abstract:

Approach. Injuries of the central nervous system (CNS) can cause serious and permanent disability due to limited regeneration ability of the CNS. Presently available therapies are focused on lesion spreading inhibition rather than on tissue regeneration. Recent investigations in the field of neural tissue engineering indicate extremely promising properties of novel injectable and non-injectable hydrogels which are tailored to serve as biodegradable scaffolds for CNS regeneration. Objective. This review discusses the state-of-the-art and barriers in application of novel polymer-based hydrogels without and with nanoparticles for CNS regeneration. Main results. Pure hydrogels suffer from lack of similarities to natural neural tissue. Many of the biological studies indicated nano-additives in hydrogels may improve their topography, mechanical properties, electroconductivity and biological functions. The most promising biomaterials which meet the requirements of CNS tissue engineering seem to be injectable thermosensitive hydrogels loaded with specific micro-and nanoparticles. Significance. We highlight injectable hydrogels with various micro-and nanoparticles, because of novelty and attractiveness of this type of materials for CNS regeneration and future development perspectives.

Keywords:

hydrogels, nanoparticles, injectable, microparticles, nanofibers, central nervous system

Affiliations:
Niemczyk B.-IPPT PAN
Sajkiewicz P.Ł.-IPPT PAN
Kołbuk D.-IPPT PAN

Conference abstracts
1.Niemczyk B., Sajkiewicz P., Gradys A., The Effect of Chemical Composition on Crosslinking Kinetics of Methylcellulose/Agarose Hydrogel, ISBPPB 2018, 4th International Conference on Biomedical Polymers and Polymeric Biomaterials, 2018-07-15/07-18, Kraków (PL), pp.174, 2018
2.Niemczyk B., Sajkiewicz P., The effect of chemical composition on viscoelastic properties of methylcellulose/agarose hydrogel, 7th KMM-VIN Industrial Workshop “Biomaterials: Key Technologies for Better Healthcare”, 2017-09-27/09-28, Erlangen (DE), pp.44, 2017
Keywords:

methylcellulose, agarose, hydrogel, cross-linking kinetics, DMA, modulus

Affiliations:
Niemczyk B.-IPPT PAN
Sajkiewicz P.-IPPT PAN