Partner: M. Parol

The John Paul’s II Western Hospital in Grodzisk Mazowiecki (PL)

Prace konferencyjne
1.Nowicki A., Trawiński Z., Gambin B., Secomski W., Szubielski M., Parol M., Olszewski R., Measurements of Flow Mediated Dilation and Shear Rate in the Radial Artery Using 20 MHz Ultrasonic System in Patients with Coronary Artery Disease., XXI Międzynarodowy Kongres Polskiego Towarzystwa Kardiologicznego. , 2017-09-21/09-23, Katowice. (PL), pp.1, 2017


A novel high-frequency scanning system, with a 20-MHz linear array transducer combined with 20-MHz pulsed Doppler, was introduced to evaluate the degree of radial artery flow-mediated dilation (FMD) and shear rate (SR)-normalized FMD (FMD/SR) after 5 min of reactive hyperaemia. In group I, comprising 27 healthy volunteers, FMD was 15 ± 4.8%, and in group II, comprising 17 patients with coronary artery disease, FMD was significantly smaller, being equal to 4.6 ± 4%. FMD/SR was equal to 5.365 ± 4.835·10-4 in group I and 1.3 ± 0.89·10-4 in group II. Statistically significant differences between the two groups were confirmed by Wilcoxon-Mann-Whitney test for FMD and FMD/SR (p-values < 0.01). AUCs of ROC curves for FMD and FMD/SR were greater than 0.9. The results confirm the usefulness of the proposed measurements of radial artery FMD and SR in differentiation of normal subjects from those with atherosclerotic lesions.

Słowa kluczowe:

flow mediated vasodilation, radial artery, shear rate, reactive hyporaemia, endothelium, pulsed Doppler, ultrasonography.

Afiliacje autorów:

Nowicki A.-IPPT PAN
Trawiński Z.-IPPT PAN
Gambin B.-IPPT PAN
Secomski W.-IPPT PAN
Szubielski M.-Mazovia Regional Hospital in Siedlce (PL)
Parol M.-The John Paul’s II Western Hospital in Grodzisk Mazowiecki (PL)
Olszewski R.-IPPT PAN