Partner: Robert Olszewski

Military Institute of Medicine (PL)

Prace konferencyjne
1.Nowicki A., Secomski W., Trawiński Z., Olszewski R., Estimation of Radial Artery Reactive Response using 20 MHz Ultrasound., 10th EAA International Symposium on Hydroacoustics, 2016-05-17/05-16, Jastrzębia Góra (PL), No.Archives of Acoustics, v. 41, No. 2., pp.356-357, 2016

Streszczenie:

Preceding atherosclerosis is endothelial dysfunction. There is therefore interest in the application of non-invasive clinical tools to assess endothelial function. There are commercially available ultrasound scanners to estimate Brachial Artery Reactive Response BARR by measuring the flow-mediated vasodilatation (FMD) of the brachial artery using 10–12 MHz linear array probes; however the precision in estimating of artery dilation does not exceeds 0.2 mm, far beyond the required one. We have introduced a high frequency scanning schemes; 25–35 MHz encoded (Golay) wobbling type imaging with- out Doppler (uScan developed in our lab, thick film wide bandwidth transducer, 50 microns axial resolution). In the second approach we have used 20 MHz linear scanning with 20 MHz pulsed Doppler attached to the linear array. Instead of brachial artery we have examined the radial artery where Radial Artery Reactive Response RARR was measured. The radial artery FMD were normalized using AUC of shear rate at the radial artery wall. The precision of the radial artery diameter measurements is over two times better using 20 MHz US instead of 7.5 MHz used for brachial artery FMD. The measured initial internal radial artery diameter was in range of 1.59–2.35 mm, the maximum diameter 2.01–2.60 mm was observed 40 to 55 seconds after releasing the cuff. In a limited number (14) of examined young, healthy patients the FMDSR were in the range from 7.8
to 9.9 in arbitrary units. In older patients with minor cardiac history the normalized FMDSR was clearly lower, 6.8 to 7.6.

Słowa kluczowe:

thick film transducers, atherosclerosis, flow mediated vasodilation.

Afiliacje autorów:

Nowicki A.-IPPT PAN
Secomski W.-IPPT PAN
Trawiński Z.-IPPT PAN
Olszewski R.-Military Institute of Medicine (PL)