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Abstract:
Constitutive theory of plasticity coupled with orthotropic damage for geomaterials was established in the framework of irreversible thermodynamics. Prime results include: 1) evolution laws are presented for coupled evolution of plasticity and orthotropic damage; 2) the orthotropic damage tensor is introduced into the Mohr-Coulomb criterion through homogenization. Both the degradation of shear strength and degradation of friction angle caused by damage are included in this model. The dilatancy is calculated with the so-called damage strain.

Keywords:
damage plasticity, coupling, dilatancy, geomaterial

Abstract:
We present the first automated pipeline to create an atlas of in
situ hybridization gene expression in the adult marmoset brain
in the same stereotaxic space. The pipeline consists of seg-
mentation of gene expression from microscopy images and
registration of images to a standard space. Automation of this
pipeline is necessary to analyze the large volume of data in
the genome-wide whole-brain dataset, and to process images
that have varying intensity profiles and expression patterns
with minimal human bias. To reduce the number of labelled
images required for training, we develop a semi-supervised
segmentation model. We further develop an iterative algo-
rithm to register images to a standard space, enabling com-
parative analysis between genes and concurrent visualization
with other datasets, thereby facilitating a more holistic under-
standing of primate brain structure and function.

Keywords:
contrastive learning, gene atlas, segmen-tation, semi-supervised learning, registration