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Bandzerewicz A.♦, Wierzchowski K.♦, Mierzejwska J.♦, Denis P., Gołofit T.♦, Patrycja S.♦, Pilarek M.♦, Gadomska-Gajadhur A.♦, Biological Activity of Poly(1,3-propanediol citrate) Films andNonwovens: Mechanical, Thermal, Antimicrobial, andCytotoxicity Studies,
Macromolecular Rapid Communications, ISSN: 1521-3927, DOI: 10.1002/marc.202300452, Vol.45, pp.1-18, 2024 Abstract:
Polymers are of great interest for medical and cosmeceutical applications. Thecurrent trend is to combine materials of natural and synthetic origin in orderto obtain products with appropriate mechanical strength and goodbiocompatibility, additionally biodegradable and bioresorbable. Citric acid,being an important metabolite, is an interesting substance for the synthesis ofmaterials for biomedical applications. Due to the high functionality of themolecule, it is commonly used in biomaterials chemistry as a crosslinkingagent. Among citric acid-based biopolyesters, poly(1,8-octanediol citrate) isthe best known. It shows application potential in soft tissue engineering. Thiswork focuses on a much less studied polyester, poly(1,3-propanediol citrate).Porous and non-porous materials based on the synthesized polyesters areprepared and characterized, including mechanical, thermal, and surfaceproperties, morphology, and degradation. The main focus is on assessing thebiocompatibility and antimicrobial properties of the materials. Keywords:
biomaterials, cell cultures, citric acid polyesters, electrospinning, , , Affiliations:
| Bandzerewicz A. | - | other affiliation | | Wierzchowski K. | - | other affiliation | | Mierzejwska J. | - | other affiliation | | Denis P. | - | IPPT PAN | | Gołofit T. | - | other affiliation | | Patrycja S. | - | other affiliation | | Pilarek M. | - | other affiliation | | Gadomska-Gajadhur A. | - | Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL) |
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