Institute of Fundamental Technological Research
Polish Academy of Sciences

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F. Baribeau

National Optics Institute (CA)


Recent publications
1.  Spinelli L., Botwicz M., Żołek N., Kacprzak M., Milej D., Sawosz P., Liebert A., Weigel U., Durduran T., Foschum F., Kienle A., Baribeau F., Leclair S., Bouchard J.P., Noiseux I., Gallant P., Mermut O., Farina A., Pifferi A., Torricelli A., Cubeddu R., Ho H.C., Mazurenka M., Wabnitz H., Klauenberg K., Bodnar O., Elster C., Bénazech-Lavoué M.Y., Bérubé-Lauzière Y., Lesage F., Khoptyar D., Subash A.A., Andersson-Engels S., Di Ninni P., Martelli F., Zaaccanti G., Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink, BIOMEDICAL OPTICS EXPRESS, ISSN: 2156-7085, DOI: 10.1364/BOE.5.002037, Vol.5, No.7, pp.2037-2053, 2014

Abstract:
A multi-center study has been set up to accurately characterize the optical properties of diffusive liquid phantoms based on Intralipid and India ink at near-infrared (NIR) wavelengths. Nine research laboratories from six countries adopting different measurement techniques, instrumental set-ups, and data analysis methods determined at their best the optical properties and relative uncertainties of diffusive dilutions prepared with common samples of the two compounds. By exploiting a suitable statistical model, comprehensive reference values at three NIR wavelengths for the intrinsic absorption coefficient of India ink and the intrinsic reduced scattering coefficient of Intralipid-20% were determined with an uncertainty of about 2% or better, depending on the wavelength considered, and 1%, respectively. Even if in this study we focused on particular batches of India ink and Intralipid, the reference values determined here represent a solid and useful starting point for preparing diffusive liquid phantoms with accurately defined optical properties. Furthermore, due to the ready availability, low cost, long-term stability and batch-to-batch reproducibility of these compounds, they provide a unique fundamental tool for the calibration and performance assessment of diffuse optical spectroscopy instrumentation intended to be used in laboratory or clinical environment. Finally, the collaborative work presented here demonstrates that the accuracy level attained in this work for optical properties of diffusive phantoms is reliable.

Affiliations:
Spinelli L. - Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie (IT)
Botwicz M. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
Żołek N. - other affiliation
Kacprzak M. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
Milej D. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
Sawosz P. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
Liebert A. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
Weigel U. - ICFO, Institut de Ciències Fotòniques (ES)
Durduran T. - ICFO, Institut de Ciències Fotòniques (ES)
Foschum F. - Universit at Ulm (DE)
Kienle A. - Universit at Ulm (DE)
Baribeau F. - National Optics Institute (CA)
Leclair S. - National Optics Institute (CA)
Bouchard J.P. - National Optics Institute (CA)
Noiseux I. - National Optics Institute (CA)
Gallant P. - National Optics Institute (CA)
Mermut O. - National Optics Institute (CA)
Farina A. - Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie (IT)
Pifferi A. - Consiglio Nazionale delle Ricerche–Istituto di Fotonica e Nanotecnologie (IT)
Torricelli A. - Politecnico di Milano (IT)
Cubeddu R. - Politecnico di Milano (IT)
Ho H.C. - Industrial Technology Research Institute (TW)
Mazurenka M. - Physikalisch-Technische Bundesanstalt (DE)
Wabnitz H. - Physikalisch-Technische Bundesanstalt (DE)
Klauenberg K. - Physikalisch-Technische Bundesanstalt (DE)
Bodnar O. - PTB, Physikalisch-Technische Bundesanstalt (DE)
Elster C. - Physikalisch-Technische Bundesanstalt (DE)
Bénazech-Lavoué M.Y. - Université de Sherbrooke (CA)
Bérubé-Lauzière Y. - Université de Sherbrooke (CA)
Lesage F. - École Polytechnique de Montreal (CA)
Khoptyar D. - Lund University (SE)
Subash A.A. - Lund University (SE)
Andersson-Engels S. - Lund University (SE)
Di Ninni P. - University of Florence (IT)
Martelli F. - University of Florence (IT)
Zaaccanti G. - University of Florence (IT)

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