Instytut Podstawowych Problemów Techniki
Polskiej Akademii Nauk

Partnerzy

M. Wrzecionek



Ostatnie publikacje
1.  Kołbuk D., Jeznach O., Wrzecionek M., Gadomska-Gajadhur A., Poly(glycerol succinate) as an eco-friendly component of PLLA and PLCL fibres towards medical applications, Polymers, ISSN: 2073-4360, DOI: 10.3390/polym12081731, Vol.12, No.8, pp.1731-1-17, 2020

Streszczenie:
This study was conducted as a first step in obtaining eco-friendly fibres for medical applications using a synthesised oligomer poly(glycerol succinate) (PGSu) as an additive for synthetic poly(L-lactic acid) (PLLA) and poly (L-lactide-co-caprolactone) (PLCL). The effects of the oligomer on the structure formation, morphology, crystallisation behaviour, and mechanical properties of electrospun bicomponent fibres were investigated. Nonwovens were investigated by means of scanning electron microscopy (SEM), wide angle X-ray scattering (WAXS), differential scanning calorimetry (DSC), and mechanical testing. The molecular structure of PLLA fibres is influenced by the presence of PGSu mainly acting as an enhancer of molecular orientation. In the case of semicrystalline PLCL, chain mobility was enhanced by the presence of PGSu molecules, and the crystallinity of bicomponent fibres increased in relation to that of pure PLCL. The mechanical properties of bicomponent fibres were influenced by the level of PGSu present and the extent of crystal formation of the main component. An in vitro study conducted using L929 cells confirmed the biocompatible character of all bicomponent fibres.

Słowa kluczowe:
poly(glycerol succinate), plasticiser, eco-friendly polymer, electrospinning, hyperbranched polyester

Afiliacje autorów:
Kołbuk D. - IPPT PAN
Jeznach O. - IPPT PAN
Wrzecionek M. - inna afiliacja
Gadomska-Gajadhur A. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
100p.
2.  Denis P., Wrzecionek M., Gadomska‐Gajadhur A., Sajkiewicz P., Poly(glycerol sebacate)–poly(l-lactide) nonwovens. Towards attractive electrospun material for tissue engineering, Polymers, ISSN: 2073-4360, DOI: 10.3390/polym11122113, Vol.11, No.12, pp.2113-1-26, 2019

Streszczenie:
Two types of poly(glycerol sebacate) (PGS) prepolymers were synthesized and electrospun with poly(l-lactic acid) (PLA), resulting in bicomponent nonwovens. The obtained materials were pre-heated in a vacuum, at different times, to crosslink PGS and investigate morphological and structural dependencies in that polymeric, electrospun system. As both PGS and PLA are sensitive to pre-heating (crosslinking) conditions, research concerns both components. More interest is focused on the properties of PGS, considering further research for mechanical properties and subsequent experiments with PGS synthesis. Electrospinning of PGS blended with PLA does not bring difficulties, but obtaining elastomeric properties of nonwovens is problematic. Even though PGS has many potential advantages over other polyesters when soft tissue engineering is considered, its full utilization via the electrospinning process is much harder in practice. Further investigations are ongoing, especially with the promising PGS prepolymer with a higher esterification degree and its variations.

Słowa kluczowe:
electrospinning, degradable polymers, synthesis, structure, crosslinking

Afiliacje autorów:
Denis P. - IPPT PAN
Wrzecionek M. - inna afiliacja
Gadomska‐Gajadhur A. - Nałęcz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences (PL)
Sajkiewicz P. - IPPT PAN
100p.

Abstrakty konferencyjne
1.  Denis P., Sajkiewicz P., Wrzecionek M., Gadomska-Gajadhur A., Poly(glycerol sebacate) – Poly(L-Lactide) nonwovens. Towards attractive electrospun material for tissue engineering, TERMIS EU 2019, TERMIS European Chapter Meeting 2019, Tissue Engineering Therapies: From Concept to Clinical Translation & Commercialisation, 2019-05-27/05-31, Rodos (GR), pp.1621-1621, 2019
2.  Jeznach O., Wrzecionek M., Ruskowski P., Gadomska-Gajadhur A., Kołbuk D., Effect of poly(glycerol succinate) addition on properties of PLA electrospun fibres, ESB2018, 29th European Conference on Biomaterials, 2018-09-09/09-13, Maastricht (NL), pp.1084-1085, 2018

Patenty
Numer/data zgłoszenia patentowego
Ogłoszenie o zgłoszeniu patentowym
Twórcy
Tytuł
Kraj i Nazwa uprawnionego z patentu
Numer patentu
Ogłoszenie o udzieleniu patentu
pdf
426830
2018-08-28
BUP 06/2020
2020-03-09
Gadomska-Gajadhur A., Ruśkowski P., Synoradzki L., Wrzecionek M., Kołbuk-Konieczny D., Jeznach O., Budnicka M., Szymaniak M.
Sposób otrzymywania poli(bursztynianiu glicerolu)
PL, Politechnika Warszawska
-
-
-

Kategoria A Plus

IPPT PAN

logo ippt            ul. Pawińskiego 5B, 02-106 Warszawa
  +48 22 826 12 81 (centrala)
  +48 22 826 98 15
 

Znajdź nas

mapka
© Instytut Podstawowych Problemów Techniki Polskiej Akademii Nauk 2021