Instytut Podstawowych Problemów Techniki
Polskiej Akademii Nauk


S. Rumiński

Medical University of Warsaw (PL)

Ostatnie publikacje
1.  Sajkiewicz P., Heljak M.K., Gradys A., Choińska E., Rumiński S., Jaroszewicz T., Bissenik I., Święszkowski W., Degradation and related changes in supermolecular structure of poly(caprolactone) in vivo conditions, Polymer Degradation and Stability, ISSN: 0141-3910, DOI: 10.1016/j.polymdegradstab.2018.09.023, Vol.157, pp.70-79, 2018

The degradation in vivo and its effect on the supermolecular structure of poly(caprolactone) was examined. Poly(caprolactone) (PCL) samples were prepared in the form of porous scaffolds implanted into rat calvarial defects. The degradation was investigated by means of gel permeation chromatography, wide angle X-ray scattering (WAXS), scanning electron microscopy (SEM) and differential scanning calorimetry (DSC). The study showed that the observed decrease of PCL crystallinity during degradation is accompanied by reduction of crystal size and/or perfection. The observed phenomenon could be explained by the presence of the high content of the low mobile fraction of investigated polymer, consisting not only almost 50% of crystal fraction but also most probably relatively high fraction of s.c. rigid amorphous fraction (RAF). Considering the type of structure characterized by the dominance of low mobile fraction, it is expected that the degradation will mainly concern these fractions, which in turn will lead to a decrease in the degree of crystallinity as well as crystal size and/or perfection.

Słowa kluczowe:
PCL degradation, In-vivo conditions, Crystallinity, Rigid amorphous fraction

Afiliacje autorów:
Sajkiewicz P. - IPPT PAN
Heljak M.K. - Warsaw University of Technology (PL)
Gradys A. - IPPT PAN
Choińska E. - Warsaw University of Technology (PL)
Rumiński S. - Medical University of Warsaw (PL)
Jaroszewicz T. - Warsaw University of Technology (PL)
Bissenik I. - Warsaw University of Life Sciences (PL)
Święszkowski W. - inna afiliacja

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