Instytut Podstawowych Problemów Techniki
Polskiej Akademii Nauk


Dongkyu Lee

Ostatnie publikacje
1.  Achadu Ojodomo J., Nwaji N., Lee D., Lee J., Akinoglu E.M., Giersig M., Park Enoch Y., 3D hierarchically porous magnetic molybdenum trioxide@gold nanospheres as a nanogap-enhanced Raman scattering biosensor for SARS-CoV-2, Nanoscale Advances, ISSN: 2516-0230, DOI: 10.1039/d1na00746g, Vol.4, pp.871-883, 2022

The global pandemic of COVID-19 is an example of how quickly a disease-causing virus can take root and threaten our civilization. Nowadays, ultrasensitive and rapid detection of contagious pathogens is in high demand. Here, we present a novel hierarchically porous 3-dimensional magnetic molybdenum trioxide–polydopamine-gold functionalized nanosphere (3D mag-MoO3–PDA@Au NS) composed of plasmonic, semiconductor, and magnetic nanoparticles as a multifunctional nanosculptured hybrid. Based on the synthesized 3D mag-MoO3–PDA@Au NS, a universal “plug and play” biosensor for pathogens is proposed. Specifically, a magnetically-induced nanogap-enhanced Raman scattering (MINERS) detection platform was developed using the 3D nanostructure. Through a magnetic actuation process, the MINERS system overcomes Raman signal stability and reproducibility challenges for the ultrasensitive detection of SARS-CoV-2 spike protein over a wide dynamic range up to a detection limit of 10−15 g mL−1. The proposed MINERS platform will facilitate the broader use of Raman spectroscopy as a powerful analytical detection tool in diverse fields.

Afiliacje autorów:
Achadu Ojodomo J. - inna afiliacja
Nwaji N. - inna afiliacja
Lee D. - inna afiliacja
Lee J. - Lexington High School (US)
Akinoglu E.M. - University of Melbourne (AU)
Giersig M. - IPPT PAN
Park Enoch Y. - inna afiliacja

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